Stem Cell Treatment for Cerebral Palsy

Revolutionizing cerebral palsy treatment with advanced stem cell therapy and tailored therapies to unlock new possibilities for improvement and quality of life.

OUR COMPANY

CELLAAX is a clinical-stage biopharmaceutical company engaged in the discovery, research, development and commercialization of Regenerative Medicine.

Cerebral Palsy

Is Stem Cell Therapy the Future of Cerebral Palsy Treatment?

For those living with cerebral palsy, the search for effective treatments has often been met with limited options focused solely on symptom management. Stem cell therapy offers a revolutionary alternative—targeting the root causes of cerebral palsy by repairing damaged brain cells and promoting regeneration. This cutting-edge approach offers improved functionality and a better quality of life.

Patient Outcome Data

The table below presents the findings from a questionnaire completed by 229 patients who received stem cell treatment with Beike Cell Therapy for Cerebral Palsy. This survey was designed to gather insights into patient satisfaction, the perceived effectiveness of the stem cell treatment, and any potential areas of improvement.

The responses have been collated and organized to provide a comprehensive overview of the patients’ experiences and outcomes.

We invite you to review the table for a detailed exploration of the results and the emerging patterns from the patient feedback.

This data was last updated on the 14th May 2025

% of Patients who noticed Improvement % of Patients who noticed a Small Improvement % of Patients who noticed a Moderate Improvement % of Patients who noticed a Large Improvement
Trunk muscle strength 88% 34% 33% 21%
Range of movement 86% 34% 34% 18%
Limb muscle strength 83% 37% 25% 21%
Spasticity 84% 37% 31% 16%
Appetite 83% 26% 25% 32%
Head control 88% 32% 32% 24%
Swallowing 79% 33% 22% 23%
Balance 79% 35% 27% 10%
Speech (babbling for infants) 78% 38% 24% 17%
Drooling 70% 30% 22% 18%
Involuntary movements 79% 38% 28% 14%
Mood disorder 76% 30% 26% 20%
Learning disability 71% 35% 23% 14%
Standing up 58% 27% 23% 8%
Walking 54% 26% 14% 14%
Crawling 47% 24% 16% 7%
Bladder control 51% 22% 16% 18%
Do you feel as though your stem cell treatment has improved the quality of life?
No 11%
Yes, has slightly improved 39%
Yes, has moderately improved 23%
Yes, has significantly improved 27%
% of patients with some level of positive result 89%
Are you currently satisfied with the outcome of the treatment?
No 4%
No comment 9%
Somewhat satisfied 33%
Yes 55%
% of patients a positive level of satisfaction 88%
Are you currently experiencing any improvements in your general physical condition?
No12%
Yes, moderate improvements41%
Yes, significant improvements29%
Yes, small improvements20%
% of Patients with ongoing improvements88%

How stem cell therapy works in Cerebral Palsy

Cerebral palsy (CP), also first known as Little’s disease, is the most common cause of physical disability in children. It affects 2 to 3 children out of every 1000 live births.

Despite the current lack of a curative treatment, with the majority of treatments only providing limited benefit (1, 2), stem cell therapy has been emerging as a novel yet effective treatment for CP; with it possibly reversing some of the original brain damage incurred during brain maturation (3-5).

Stem cell therapy has been shown to benefit at least 85% of CP patients treated, with the best improvement being seen in muscle tone, and almost half of the patients showing moderate to significant neurological improvement (5, 6). Cerebral Palsy is actually one of several conditions that have been scientifically proven to respond positively to stem cell treatment as we will discuss.

Stem cell treatment involves the injection of immature stem cells that are basically the origin of all the cells within our bodies. Stem cells can differentiate into different cell lines, therefore replacing degenerating and damaged cells – such as the oligodendrocytes in cerebral palsy – with healthy ones from a healthy donor. Stem cells can differentiate into lots of cell lineages including skin, bone, hair, cartilage, neurons, muscles, fat cells, liver, etc. (3).

In the case of CP and other neurological disorders, they also offer additional neuroprotection, i.e. preventing the already-ongoing process of neurological degeneration through (3, 11):

  • Increasing the production of neurotrophic factors that promote nervous cell proliferation and differentiation (ex. glia-derived neurotrophic factor (GDNF) and brain-derived neurotrophic factor (BDNF))
  • Increasing the number of oligodendrocytes, which are defective in patients with CP, to allow proper brain myelination
  • Modulating your immune system and the ongoing inflammatory process – thereby reducing the ongoing neurodestructive process
  • Promoting vascular supply to the nervous system through stimulating the generation of new blood vessels (neovascularization)
  • Stimulating neuroplasticity/brain connectivity by increasing the number of synaptic connections
  • Increasing the number of the brain’s microglia which are responsible for repairing brain damage and preserving normal brain tissue
  • Reducing free radicals and reactive oxygen species production that could have detrimental effects on the nervous system (including the induction of neuron-cell apoptosis/death)
What are the Benefits of Stem Cell Therapy in Cerebral Palsy

The efficacy of stem cell transplantation reaches as high as 85% – which is a dramatic improvement from the currently-used treatments. It can repair and stop the ongoing neurological destructive process, and it might even reverse the original brain insult responsible for CP. Stem cells have proven benefits in improving (4, 5):

  • Gross motor functions: Such as walking, jumping, kneeling, sitting, and crawling
  • Fine motor functions: Such as different hand functions
  • Muscle tone: Muscle tone significantly decreases after stem cell therapy – therefore allowing better range of motion
  • Cognitive functions: Such as alertness and concentration
  • Speech and language
  • Swallowing and drooling
  • Self-dependence
  • Social-adaptability
  • Visual acuity
  • Psychiatric and physical health: Including better mood

Although stem cell therapy provides significant benefits in CP as mentioned, it should still be used in combination with other treatment modalities including physiotherapy; psychiatric therapy; and speech therapy – all of which are available at Beike Technology – in order to achieve the highest possible response out of treatment.

Side Effects and Factors Affecting Response to Stem Cell Therapy

Stem cell therapy has limited side effects if used correctly, with comparable side effect risks to those associated with regular blood transfusion (ex. allergic reactions or fever). Also, given that this might be a difficult decision to make, and you might need to weigh the benefits versus risks prior to starting this journey, we will discuss with you different factors that might affect your child’s response to stem cell therapy, and how we at Beike Technology address each factor to ensure that we provide you with the highest efficacy using the safest procedure possible (7, 12).

  • Dose/Number of stem cells: The higher the dose of stem cells – within limits of course – the better the response. At Beike Technology, we administer an optimum dose of around 120-400 Million Cells (depending on the child’s weight).
  • Route/Method of administration: Studies have shown that intrathecal injection (through lumbar puncture directly within the brain’s CSF) provides a better response than the traditional intravenous route (which causes stem cells to go to other organs than the brain before reaching it). At Beike Technology, we use both intravenous and intrathecal routes concomitantly in order to obtain maximal efficacy; while ensuring the least possible side effects of toxicity.
  • Age of transplant: There is some suggestion that the younger age of intervention has better results to stem cell therapy.
  • Type of Stem Cells used: As previously mentioned, umbilical cord-based stem cells have better-proven efficacy in CP compared to other types of stem cells. At Beike Technology, we use both forms of umbilical cord-based samples in patients with CP; umbilical cord blood and umbilical cord tissue.
  • Follow-up Time: Significant benefits from stem cell therapy begin appearing around three months after stem cell therapy, and most people reach their full potential around 6-12 months after treatment. At Beike Technology, even after discharge, we provide you with a full follow-up program beginning as early as one month and up to one year after transplantation. You have complete access to our professional team even after you leave our center.
Possible improvements after Stem Cell Therapy for Cerebral Palsy

The purpose of the treatment is to promote healing of the original brain injury in order to restore neurological function. Thus, various kinds of improvement are possible after our treatment. The majority of Cerebral Palsy patients that have been treated by Beike, utilizing the combination of stem cell therapy and rehabilitation, showed visible signs of improvements, especially for these symptoms*:

  • Spasticity
  • Speech
  • Balance
  • Learning
  • Head control
  • Range of movement
  • Walking
  • Swallowing
  • Mood disorder
  • Drooling and appetite


*It is important to remember that as for any medical treatment, improvements cannot be guaranteed. Please contact us for more information regarding the possible improvements for a particular case