Natural Killer Cells Therapy

Natural Killer Cells

Natural killer (NK) cells are immune cells of the innate immunity which are the first responders in the immune system. They eliminate and control tumors, and microbial infections by limiting their spread and subsequent tissue damage. They also play pivotal functions in cancer immune surveillance by eliminating cancer or abnormal cells without harming the healthy cells.

Types of Cancer Treatment
Conventional Therapy

            

Conventional Therapy
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Surgery

Cancer surgery to
remove tumor

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Chemotherapy and
Radiotherapy

Cytotoxic drugs and radiation

            

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Antitumor Immunotherapy

• Natural Killer (NK) cell-based therapy
• CAR-T cell therapy
• CAR-NK therapy

CELLAAX Natural Killer Cells
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Cell Based-Immunotherapy
To Utilizes your own body’s immune defences to fight off cancer.

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What we offer?
Pure Natural Killer (NK) cells Memory-Like Natural Killer cells (IMMUNAAX)

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Our Goal
To expand and to maximize the ability of Natural Killer cells in eliminating cancer.

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How it works?
Natural Killer (NK) cells recognize and attack cancer cells specifically.

NK Cells vs IMMUNAAX
Natural Killer (NK) Cell

            

Memory-like NK Cells (IMMUNAAX)
Cancer Fighting NK Cells with “MEMORY”

Lymphocyte of the innate immunity

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Enhanced cancer cell recognition

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Function

Eliminate virally infected cells, cancer cells & abnormal cells

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Enhanced cancer fight capacity

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Response rate

Rapid and immediate

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Potentially providing longer lasting effects

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Why Cell-Based Immunotherapy?
SS 1

Highly Selective

Targets cancer cells specifically without affecting healthy cells
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Fewer Side Effects

Enhances immunity, improves quality of life
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Effectiveness

                                

Proven efficacy in refractory diseases Detect and control early signs of cancer
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Biocompatibility

No rejection and no major complications
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Application

Non-invasive and high adaptation
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Remission

Lower chances of relapse
CAR-T vs IMMUNAAX
CAR-T

            

IMMUNAAX

Type of cells: T cells Gene editing
• To express Chimeric Antigen Receptor (CAR)
• Require antigen recognition prior to killing cancer cells

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Mechanism

Type of cells: Natural killer cells Cytokine induced
• To become Memory-like NK cells
Generate immediate
esponse to attack cancer
cells

Blood cancers
• Multiple myeloma • Follicular lymphoma • Mantle cell lymphoma • Acute Lymphoblastic Leukaemia (ALL)
• Diffuse large B-cell lymphoma (DLBCL)

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Types of cancer (Clinical Studies)

Blood and solid cancers:
• Melanoma • Ovarian cancer • Hepatocellular carcinoma • Acute Myeloid Leukaemia (AML) • Acute Lymphoblastic Leukaemia (ALL)

Blood cancers
• Multiple myeloma • Follicular lymphoma • Mantle cell lymphoma • Acute Lymphoblastic Leukaemia (ALL)
• Diffuse large B-cell lymphoma (DLBCL)

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Possible side effects

Blood and solid cancers:
• Melanoma • Ovarian cancer • Hepatocellular carcinoma • Acute Myeloid Leukaemia (AML) • Acute Lymphoblastic Leukaemia (ALL)

How IMMUNAAX Works?
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Collection

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Expansion

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Stimulation

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Infusion

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Elimination

Patient’s blood is collected to obtain white blood cells.

Retrieved NK cells undergo selection and expansion process.

To amplify their cancer recognition system prior infusion.

Exclusive ML-NK cells are infused back into patient’s body.

ML-NK cells target and eliminate cancer cells in the system.

Improved Natural Killer Cells