Natural Killer Cells Therapy
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Natural Killer Cells
Natural killer (NK) cells are immune cells of the innate immunity which are the first responders in the immune system. They eliminate and control tumors, and microbial infections by limiting their spread and subsequent tissue damage. They also play pivotal functions in cancer immune surveillance by eliminating cancer or abnormal cells without harming the healthy cells.
Types of Cancer Treatment
Conventional Therapy
Conventional Therapy
Surgery
Cancer surgery to
remove tumor
Chemotherapy and
Radiotherapy
Cytotoxic drugs and radiation
Antitumor Immunotherapy
• Natural Killer (NK) cell-based therapy
• CAR-T cell therapy
• CAR-NK therapy
CELLAAX Natural Killer Cells
Cell Based-Immunotherapy
To Utilizes your own body’s immune defences to fight off cancer.
What we offer?
Pure Natural Killer (NK) cells Memory-Like Natural Killer cells (IMMUNAAX)
Our Goal
To expand and to maximize the ability of Natural Killer cells in eliminating cancer.
How it works?
Natural Killer (NK) cells recognize and attack cancer cells specifically.
NK Cells vs IMMUNAAX
Natural Killer (NK) Cell
Memory-like NK Cells (IMMUNAAX) Cancer Fighting NK Cells with “MEMORY”
Lymphocyte of the innate immunity
Enhanced cancer cell recognition
Function
Eliminate virally infected cells, cancer cells & abnormal cells
Enhanced cancer fight capacity
Response rate
Rapid and immediate
Potentially providing longer lasting effects
Why Cell-Based Immunotherapy?
Highly Selective
Targets cancer cells specifically without affecting healthy cells
Fewer Side Effects
Enhances immunity, improves quality of life
Effectiveness
Proven efficacy in refractory diseases Detect and control early signs of cancer
Biocompatibility
No rejection and no major complications
Application
Non-invasive and high adaptation
Remission
Lower chances of relapse
CAR-T vs IMMUNAAX
CAR-T
IMMUNAAX
Type of cells: T cells Gene editing
• To express Chimeric Antigen Receptor (CAR)
• Require antigen recognition prior to killing cancer cells
Mechanism
Type of cells: Natural killer cells Cytokine induced
• To become Memory-like NK cells
• Generate immediate
esponse to attack cancer
cells
Blood cancers
• Multiple myeloma • Follicular lymphoma • Mantle cell lymphoma • Acute Lymphoblastic Leukaemia (ALL)
• Diffuse large B-cell lymphoma (DLBCL)
Types of cancer (Clinical Studies)
Blood and solid cancers:
• Melanoma • Ovarian cancer • Hepatocellular carcinoma • Acute Myeloid Leukaemia (AML) • Acute Lymphoblastic Leukaemia (ALL)
Blood cancers
• Multiple myeloma • Follicular lymphoma • Mantle cell lymphoma • Acute Lymphoblastic Leukaemia (ALL)
• Diffuse large B-cell lymphoma (DLBCL)
Possible side effects
Blood and solid cancers:
• Melanoma • Ovarian cancer • Hepatocellular carcinoma • Acute Myeloid Leukaemia (AML) • Acute Lymphoblastic Leukaemia (ALL)
How IMMUNAAX Works?
Collection
Expansion
Stimulation
Infusion
Elimination
Patient’s blood is collected to obtain white blood cells.
Retrieved NK cells undergo selection and expansion process.
To amplify their cancer recognition system prior infusion.
Exclusive ML-NK cells are infused back into patient’s body.
ML-NK cells target and eliminate cancer cells in the system.