Stem Cell Therapy for Muscular Dystrophy

A combined approach of supportive therapies with stem cells giving patients real chances of improvement

OUR COMPANY

CELLAAX is a clinical-stage biopharmaceutical company engaged in the discovery, research, development and commercialization of Regenerative Medicine.

Muscular Dystrophy

Are You Considering Stem Cell Treatment for Muscular Dystrophy?

Muscular dystrophies are inherited muscle disorders that have limited curative treatment options, with most only focusing on delaying disease progression and preventing further muscle damage or risk of respiratory infections in order to ensure a better quality-of-life for such individuals. Stem Cell Treatment however offers hope, with studies showing stem cell therapy can improve different muscular functions which are impaired in different forms of muscular dystrophies.

Read on to see if Muscular Dystrophy Stem Cell Treatment might be right for you.

 

Muscular Dystrophy Patient Outcome Data

The table below presents the findings from a questionnaire completed by 43 patients who underwent stem cell treatment with Cellax Therapy for Muscular Dystrophy. This survey aimed to capture insights regarding patient satisfaction, the perceived effectiveness of the stem cell treatment, and any potential areas of enhancement.

The collected responses have been systematically arranged to offer a thorough overview of the patients’ experiences and outcomes.

This data last updated on the 5th of December 2024

% of Patients who noticed Improvement % of Patients who noticed a Small Improvement % of Patients who noticed a Moderate Improvement % of Patients who noticed a Large Improvement
Body pain 87% 42% 21% 24%
Muscle stiffness 83% 32% 32% 7%
Enlarged muscles 74% 37% 21% 16%
Loss of muscle mass 71% 24% 24% 17%
Muscle cramps 77% 27% 23% 27%
Walking 70% 43% 23% 4%
Falls 72% 32% 19% 19%
Standing up 64% 36% 26% 2%
Heart palpitations or arrhythmias 79% 26% 26% 26%
Development delay (children) 71% 24% 18% 29%
Excessive sleeping or sleepiness 58% 21% 25% 13%
Difficulty swallowing 73% 27% 13% 33%
Slurred speech 67% 7% 27% 33%
Behaviour problems (children) 53% 0% 13% 40%
Walking up stairs 43% 26% 11% 6%
Cognitive impairment 46% 8% 8% 30%
Droopy eye lids 40% 0% 20% 20%

The purpose of our stem cell treatment is to restore neurological function in the brain/spinal cord lesion area, thus, various kinds of improvement are possible after our treatment and our past patients have experienced the following*:

Do you feel as though your stem cell treatment has improved the quality of life?
No15%
Yes, has slightly improved30%
Yes, has moderately improved21%
Yes, has significantly improved34%
% of patients with some level of positive result85%

The purpose of our stem cell treatment is to restore neurological function in the brain/spinal cord lesion area, thus, various kinds of improvement are possible after our treatment and our past patients have experienced the following*:

Are you currently satisfied with the outcome of the treatment?
No 8%
No comment 14%
Somewhat satisfied 20%
Yes 57%
% of patients a positive level of satisfaction 77%
Are you currently experiencing any improvements in your general physical condition?
No 16%
Yes, small improvements 35%
Yes, moderate improvements 22%
Yes, significant improvements 27%
% of Patients with ongoing improvements 82%
How Stem Cell Therapy Improves Symptoms of Retinal or Optic Nerve Disorders

Stem cells are “pluripotent,” meaning they can differentiate into all other cells due to their self-renewing abilities. They can develop into ectodermal (ex., skin, and some neurological structures), mesodermal (ex., bones, cartilage, and blood cells), or endodermal cells (ex., cells of internal body organs).

Therefore, injecting stem cells – from a donor – should theoretically allow them to differentiate and “replace” the damaged retina or optic nerve seen in different ophthalmological disorders. Stem cell therapy has provided new hope in curing or at least improving the sight-related symptoms associated with retinal or optic degeneration in order to provide patients with a better quality of life. Following the testing of stem cell treatment on people with retinal and/or optic nerve atrophy, in addition to their self-renewing abilities, stem cells have proven to have additional benefits other than tissue replacement.

  • Replacing and repairing the damaged optic cells: As mentioned, this is their original function; to replace the damaged tissue – i.e. retinal cells in case of retinal damage and optic neurons in case of optic nerve atrophy – through the conversion of one cell type to another.
  • Increasing the production of neurotrophic factors that promote nervous cell proliferation and differentiation (ex. glia derived neurotrophic factor (GDNF) and brain derived neurotrophic factor (BDNF)). These factors can locally enhance cellular recruitment, proliferation and maturation within the damaged or affected retinal/optic nerve neurons.
  • Modulating the immune system and the ongoing inflammatory process: Stem cells produce different antioxidants; thereby reducing the neurodestructive and atrophic process characterizing retinal degeneration and optic nerve atrophy.
  • Preventing cell death: Through releasing substances that can inhibit the process of apoptosis, or programmed cell death, of the damaged cells until they are adequately repaired by stem cells.
Benefits of Stem Cell Therapy in Optic Nerve Atrophy and Retinal Disorders

The purpose of our stem cell treatment for optic nerve hypoblasia/septo optic dysplasia is to restore neurological function in the brain area and in the optical nerve. Various kinds of improvement are possible after our comprehensive treatment. Past patients have experienced the following improvements*:

  • Sharpened visual acuity
  • Enlarged visual field
  • Reduced nystagmus
  • Improved hormonal deficiences
  • Enhanced light perception
  • Brighter night vision
  • Improved strabismus
  • Decreased autistic symptoms

 

*It is important to remember that as for any medical treatment, improvements cannot be guaranteed. Please contact us for more information regarding the possible improvements for a particular case.